A 15-year-old female high school softball player with no prior history of either shoulder or elbow pathologies presented with pain in the elbow of her throwing arm that progressed to her shoulder during her high school softball team’s fall season. The athlete received an MRI showing the presence of a Buford complex, a normal anatomical variation of the glenoid labrum in which the anterosuperior portion of the labrum is undeveloped in conjunction with an overdeveloped cord like middle glenohumeral ligament that originates upon the superior portion of the glenoid at the same location of the base of the biceps tendon. The athlete underwent a supervised rehabilitation program and continued athletic participation until she eventually developed glenohumeral multidirectional instability and secondary cubital tunnel syndrome with associated ulnar nerve subluxation. The athlete was managed through rehabilitation until the development of the secondary pathologies which were treated surgically. Athletic trainers and all allied health care professionals should be aware of the Buford complex, particularly if they deal with athletes in overhead sports. The Buford should be considered a predisposing factor to glenohumeral and glenoid labrum pathologies, and proper prophylactic practices may serve to reduce the incidence of injury or reinjury to the affected shoulder in these individuals.