Purpose: Injury prevention and mitigation are among the primary responsibilities of Athletic Trainers. Research has indicated that basketball players at the secondary-school level suffer up to 2.1 time loss injuries (TLI) per 1,000 athletic exposures (AE). It has been suggested that Functional Movement Screen (FMS™) composite and individual task scores may help determine injury risk. Researchers have suggested that a variety of strength and conditioning strategies may positively alter both composite and individual FMS™ task scores and reduce movement asymmetry. Methods: During a retrospective analysis of the records of all junior varsity and varsity basketball players at one secondary school over one season, no TLI was recorded over 1900 AE following the implementation of team-specific strength and conditioning programming. Results: Significant increases in pre-season and post-season composite FMS™ scores (pre-season mean = 14.33 ± 1.84; post-season mean = 16.44 ± 1.72; p < 0.001), and FMS™ individual task scores; deep squat (DS) (p < 0.001), hurdle step (HS) (p = 0.002), in-line lunge (INL) (p = .011), active straight leg raise (ASLR) (p = .02), and rotatory stability (RS) (p = .005) were noted across 27 male and female participants. Among females, composite FMS™ scores changed significantly (pre-season mean = 14.92 ± 1.38; post-season mean = 17.00 ± 1.04; p < 0.001), as did HS (p < 0.001) and INL (p = .025). Among males, significant changes were noted in composite FMS™ scores (pre-season mean = 13.87 ± 2.07; post-season mean = 16.00 ± 2.04; p < 0.001), as well as DS (p = 0.007), and RS (p = .025). Reductions in the number of scores of one and movement asymmetries were also evident during post-season FMS™ screening. Conclusions: Emphasizing movement competency and strength and conditioning training has positive effects on injury risk reduction in secondary school basketball players.