Chemistry Faculty Publications
Document Type
Article
Abstract
Metal coordination is used to alter the oligomerization state of a designed peptide structure. The 30-residue polypeptide AQ-Pal21 4Pal21 contains two metal-binding 4-pyridylalanine (Pal) residues on its solvent-exposed surface and exists as a very stable two-stranded a-helical coiled-coil. Upon the addition of Pt(en)(NO3)(2), a significant conformational change to a metal-bridged, four-helix bundle is seen.
Copyright Statement
Publisher PDF
Repository Citation
Tsurkan, Mikhail V. and Ogawa, Michael Y., "Metal-mediated Peptide Assembly: Use Of Metal Coordination To Change The Oligornerization State Of An Alpha-helical Coiled-coil" (2007). Chemistry Faculty Publications. 129.
https://scholarworks.bgsu.edu/chem_pub/129
Publication Date
8-2007
Publication Title
Inorganic Chemistry
DOI
https://doi.org/10.1021/ic700958h
Start Page No.
6849
End Page No.
6851